Agreed. I’d only elaborate a little in your fourth paragraph. Opposite-hand hitters — lefties versus righties, or vice-versa — have the advantage because they seldom have to deal with pitches that break away. When a lefty batter is up against a righty pitcher, for example, the batter knows the pitcher’s stuff won’t break away, UNLESS the pitcher has a screwball or backdoor slider. Most do not.
The world has been out to get lefties for thousands of years. And while we no longer force 10% of the population to learn to write with their right hand or burn them at the stake as witches, the odds still aren’t stacked in their favor.
If your response is to say that mouse button behaviours can be switched, don't. I've never seen a left handed person use a mouse on the left. Why? Because a mouse is simple to operate, and nearly all the hotkeys in common operating systems (Alt/Ctrl/Shift with Z/X/C/V/B/N/M/Q/W/E/R/T/A/S/D/F/G/H) can be done solely with the left hand. Left handers can use a computer two handed faster and more conveniently than right handers.
But this breakdown for left versus right in Fido as well as Coco is about 50-50, eschewing humans' overwhelmingly right-sided population-handedness. That even-handed, if you will, split extends to non-mammals such as fiddler crabs, whose enlarged claw for fighting develops on either side in equal measure.